The route is about 1 km long, lasts about 60 minutes and is of moderate difficulty. In it, the visitor with artistic interests and quests will have the opportunity to get acquainted with European and Byzantine art, as expressed in buildings of old Xanthi in the 19th century.

Starting from the Michaloglou Mansions in the district of Agios Vlasios and ending at the church of Pammegistoi Taxiarchs, one will visit the churches of old Xanthi, representative samples of the post-Byzantine period, while in the buildings of secular architecture one will admire ceiling paintings and frescoes, of the so-called Belle Époque (1871-1914).

In the old churches it is worth observing the portable icons that carry strong western iconographic influences, which are mixed with traditional Byzantine standards and follow theological concepts after the conquest. They are created either by workshops active in Thrace or northern Greece (e.g. the workshop of Ainos), or by the Mount Athos workshop (e.g. the painters Nikiforos and his student Ioasaf), or by individual painters (e.g. Nikolaos from Hasköy in Constantinople, Thassios M. Evangelidis, Patrinos Takis Prionas).

It is also worth noting the crucifix in the Church of Agios Georgios, a work of Fotis Kontoglou (1959), the embroidered icon of Archangel Michael in the Church of the Taxiarchs, the marble relief candlestand in the Church of Agios Vlasios.

On the other hand, in the rich neoclassical residences one can see works of Bavarian or German painters, such as the frescoes in the Houses of Kougioumtzoglou, Stavropoulos and Michaloglou or the goddesses from the twelve Gods, which adorn the staircase of the Metaxas House. Of interest are the ceiling paintings with decorative and floral motifs in the Daniel Mansion and the Moses Mansion, while a unique example of neoclassical sculpture in the city is the statue in the courtyard of the Church of Agios Georgios.